林尤舜 职    称：长聘教轨副教授，博士研究生导师，独立PI 所属学科：植物细胞生物学 研究方向：植物细胞器发育及其调控抗逆的分子机制研究 电子信箱：linyoushun@sjtu.edu.cn 联系地址：威斯尼斯人wns579创新B楼529B室 实验室地址：威斯尼斯人wns579创新B楼518室

 

教育和科研经历：

2021.11-至今，威斯尼斯人wns579，威斯尼斯人wns579，长聘教轨副教授

2020.12-2021.09，香港中文大学，生命科学学院，副研究员

2015.01-2020.11，香港中文大学，生命科学学院，博士研究生

2013.01-2014.12，香港中文大学，生命科学学院，硕士研究生

2011.09-2012.12，香港中文大学，生命科学学院，初级研究助理

 

主要研究领域：

在真核生物中存在保守复杂的内膜系统，主要由磷脂双分子层的生物膜组成。生物膜形成不同功能的亚细胞结构即细胞器，将细胞分割成功能不同的区域，使得各种生化反应在特定的细胞器内高效地进行，维持细胞的内稳态。植物细胞包含多种细胞器，主要分为双层膜（如自噬体、叶绿体和线粒体等）、单层膜（如液泡、内质网和高尔基体等）以及无膜细胞器（如生物分子凝聚体等）。这些细胞器对于植物的生长发育和抗逆境胁迫发挥不可或缺的功能。

本课题组以模式植物拟南芥、粮食作物水稻以及园艺作物番茄等作为材料开展研究，结合细胞生物学（超分辨显微技术，电子显微技术等）、分子生物学、遗传学和生物信息学等多种方法从亚细胞微观角度出发，探索植物细胞器响应逆境的信号通路, 解析细胞器与植物抗逆胁迫的关系，为作物抗逆改良提供重要理论基础。目前主要研究内容包括：

1. 自噬信号通路调控与自噬体形成的分子机制

2. 植物自噬信号与生长发育信号的协同调控关系

3. 植物细胞器感知热胁迫信号的通路及其抗热机制

 

 

发表论文 (#, equal contribution)：

1. Hai Zhang; Ji-Fu Zhou; Yi Kan; Jun-Xiang Shan; Wang-Wei Ye; Nai-Qian Dong; Tao Guo; You-Huang Xiang; Yi-Bing Yang; Ya-Chao Li; Huai-Yu Zhao; Hong-Xiao Yu; Zi-Qi Lu; Shuang-Qin Guo; Jie-Jie Lei; Ben Liao; Xiao-Rui Mu; Ying-Jie Cao; Jia-Jun Yu; Youshun Lin*; Hong-Xuan Lin*. A genetic module at one locus in rice protects chloroplasts to enhance thermotolerance; Science. 376(6599) (2022): 1293-1300. (* co-corresponding author)

2. Youshun Lin*, Yonglun Zeng, Ying Zhu, Jinbo Shen, Hao Ye, Liwen Jiang*. Plant Rho GTPase signaling promotes autophagy; Molecular Plant. 14(6) (2021), 905-920. (* co-corresponding author)

3. Youshun Lin, Rongfang Guo, Changyang Ji*, Jun Zhou*, Liwen Jiang*. New insights into AtNBR1 as a selective autophagy cargo receptor in Arabidopsis; Plant Signaling & Behavior; 16(1) (2021), p.1839226.

4. Yonglun Zeng, Baiying Li, Changyang Ji, Lei Feng, Fangfang Niu, Cesi Deng, Shuai Chen, Youshun Lin, Kenneth C.P. Cheung, Jinbo Shen, Kam Bo Wong, Liwen Jiang*. A unique AtSar1D-AtRabD2a nexus modulates autophagosome biogenesis in Arabidopsis thaliana; Proceedings of the National Academy of Sciences, 118(17) (2021), e2021293118.

5. Liu Hong, Fangfang Niu*, Youshun Lin, Shuang Wang, Liyuan Chen* and Liwen Jiang. MYB106 is a negative regulator and a substrate for CRL3BPM E3 ligase in regulating flowering time in Arabidopsis thaliana; Journal of Integrative Plant Biology, (2021), 1104-1119.

6. Liu Hong, Fangfang Niu*, Youshun Lin, Shuang Wang, Liyuan Chen* and Liwen Jiang. MYB117 is a negative regulator of flowering time in Arabidopsis. Plant Signaling & Behavior, (2021), 1901448.

7. Changyang Ji, Jun Zhou, Rongfang Guo, Youshun Lin, Chun Hong Kung, Shuai Hu, Wing Yin Ng, Xiaohong Zhuang, Liwen Jiang*.  AtNBR1 Is a Selective Autophagic Receptor for AtExo70E2 in Arabidopsis; Plant Physiology, 184(2) (2020), 777-791.

8. Yonglun Zeng*, Baiying Li*, Youshun Lin, Liwen Jiang*. The interplay between endomembranes and autophagy in plants; Current Opinion in Plant Biology, 52 (2019), 14-22.

9. Jinbo Shen, Caiji Gao, Qiong Zhao, Youshun Lin, Xiangfeng Wang, Xiaohong Zhuang, Liwen Jiang*. AtBRO1 functions in ESCRT-I complex to regulate multivesicular body protein sorting; Molecular Plant, 9(5) (2016), 760-763.

10. Youshun Lin#, Yu Ding#, Juan Wang, Jinbo Shen, Chun Hong Kung, Xiaohong Zhuang, Yong Cui, Zhao Yin, Yiji Xia, Hongxuan Lin, David G. Robinson, Liwen Jiang*. Exocyst-positive organelles and autophagosomes are distinct organelles in plants; Plant Physiology; 169(3) (2015), 1917-1932.

11. Chen Chen#, Hao Chen#, Youshun Lin#, Jinbo Shen, Junxiang Shan, Peng Qi, Min Shi, Meizhen Zhu, Xuehui Huang, Qi Feng, Bin Han, Liwen Jiang, Jiping Gao*, Hongxuan Lin*. A two-locus interaction causes interspecific hybrid weakness in rice; Nature Communications, 5(1) (2014), 1-11.

12. Jinbo Shen, Pui Kit Suen, Xiangfeng Wang, Youshun Lin, Sze Wan Lo, Enrique Rojo, Liwen Jiang*.  An in vivo expression system for the identification of cargo proteins of vacuolar sorting receptors in Arabidopsis culture cells; Plant Journal, 75(6) (2013), 1003-1017;

13. Peng Qi#, Youshun Lin#, Xianjun Song#, Jinbo Shen, Wei Huang, Junxiang Shan, Meizhen Zhu, Liwen Jiang, Jiping Gao*, Hongxuan Lin*. The novel quantitative trait locus GL3.1 controls rice grain size and yield by regulating Cyclin-T1;3; Cell Research, 22(12) (2012), 1666-1680.

 

 

招生和招聘：

欢迎优秀博士后，博士研究生，硕士研究生和本科生加盟，共同探索植物细胞器与抗逆境胁迫的分子调控关系！